Why in the News?

Recent research by scientists at the University of Nottingham’s has found that a chemical produced by a fungus growing on caterpillars may slow cancer cell growth.

What is Caterpillar fungus?

• Cordyceps militaris, also known as caterpillar fungus, is a parasitic fungus that primarily infects caterpillars and other insects.
• Found in the Himalayan region and parts of Asia, it is valued in traditional Asian medicine for its health benefits, including immune support, anti-inflammatory properties, and energy enhancement.
• It is considered a delicacy in some Asian cultures and has long been used for its purported wellness effects.

How it can slow down growth of cancer cells?

• Researchers from the University of Nottingham’s School of Pharmacy have identified cordycepin, a compound produced by Cordyceps militaris, as potentially effective in slowing cancer cell growth.
• Cordycepin works by interrupting overactive cell growth signals in cancer cells, which prevents rapid multiplication and allows for more targeted treatment.
• This approach may be less harmful to healthy tissues compared to conventional cancer treatments, offering a promising direction for targeted cancer therapies.

Other observations and significance of the species

• In addition to its traditional uses, Cordyceps militaris is significant for its role in ecological balance, helping control insect populations in forest ecosystems.
• Advances in research have enabled large-scale studies on cordycepin’s effects, with future studies focusing on derivatives of cordycepin for potentially enhanced anti-cancer properties.
• The fungus illustrates how natural compounds can contribute to sustainable medical practices, offering less toxic alternatives for disease treatment, especially in oncology.

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