Health Sector – UHC, National Health Policy, Family Planning, Health Insurance, etc.

Hepatitis E Virus (HEV)

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From UPSC perspective, the following things are important :

Prelims level: Hepatitis E Virus (HEV)

Why in the News?

Recent research indicates that pigs may act as a transmission vehicle for a strain of the hepatitis E virus (HEV) commonly found in rats, known as Rocahepevirus ratti, or rat HEV.

Role of Pigs in Transmission

  • HEV Reservoir: Pigs naturally carry hepatitis E virus (HEV), particularly strains that can infect humans.
  • Transmission via Pork: Humans can contract HEV by consuming raw or undercooked pork from infected pigs.
  • Environmental Contamination: Infected pigs shed HEV in faeces, contaminating the environment and water sources, potentially spreading the virus to humans.
    • Poor sanitation in pig farms facilitates HEV transmission between pigs and increases the risk of human infection through the food chain.
  • Cross-Species Transmission: Pigs may also act as intermediaries for rat HEV, transmitting the virus from rats to humans in farm environments.

About Hepatitis E Virus (HEV):

  • Hepatitis E is caused by the Hepatitis E Virus (HEV), which is a positive-sense, single-stranded, non-enveloped RNA virus.
  • HEV is classified under the family Hepeviridae, genus Orthohepevirus.
  • It was first identified during an outbreak among Soviet soldiers in Afghanistan in 1983.
  • The earliest well-documented HEV epidemic occurred in New Delhi, India, in 1955, retrospectively identified as HEV.
  • Transmission:
    • The primary route of transmission is fecal-oral, especially through contaminated water and food.
    • Zoonotic transmission is possible with genotypes 3 and 4, commonly spread through undercooked meat or direct animal contact.
  • Symptoms:
    • Jaundice, nausea, fatigue, and elevated liver enzymes.
    • Severe cases can lead to liver failure, especially in pregnant women and immunocompromised individuals.
  • Prevention and Cure:
    • A vaccine, HEV 239, is approved for use in China, but no vaccine is widely available or approved in most countries, including the United States.
    • There is no specific antiviral treatment for acute HEV.
    • Prevention relies on improved sanitation, safe drinking water, and proper food handling.

PYQ:

[2019] Which one of the following statements is not correct?

(a) Hepatitis B virus is transmitted much like HIV.

(b) Hepatitis B, unlike Hepatitis C, does not have a vaccine.

(c) Globally, the number of people infected with Hepatitis B and C viruses are several times more than those infected with HIV.

(d) Some of those infected with Hepatitis B and C viruses do not show the symptoms for many years.

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