From UPSC perspective, the following things are important :
Prelims level: Hepatitis E Virus (HEV)
Why in the News?
Recent research indicates that pigs may act as a transmission vehicle for a strain of the hepatitis E virus (HEV) commonly found in rats, known as Rocahepevirus ratti, or rat HEV.
Role of Pigs in Transmission
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About Hepatitis E Virus (HEV):
- Hepatitis E is caused by the Hepatitis E Virus (HEV), which is a positive-sense, single-stranded, non-enveloped RNA virus.
- HEV is classified under the family Hepeviridae, genus Orthohepevirus.
- It was first identified during an outbreak among Soviet soldiers in Afghanistan in 1983.
- The earliest well-documented HEV epidemic occurred in New Delhi, India, in 1955, retrospectively identified as HEV.
- Transmission:
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- The primary route of transmission is fecal-oral, especially through contaminated water and food.
- Zoonotic transmission is possible with genotypes 3 and 4, commonly spread through undercooked meat or direct animal contact.
- Symptoms:
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- Jaundice, nausea, fatigue, and elevated liver enzymes.
- Severe cases can lead to liver failure, especially in pregnant women and immunocompromised individuals.
- Prevention and Cure:
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- A vaccine, HEV 239, is approved for use in China, but no vaccine is widely available or approved in most countries, including the United States.
- There is no specific antiviral treatment for acute HEV.
- Prevention relies on improved sanitation, safe drinking water, and proper food handling.
PYQ:[2019] Which one of the following statements is not correct? (a) Hepatitis B virus is transmitted much like HIV. (b) Hepatitis B, unlike Hepatitis C, does not have a vaccine. (c) Globally, the number of people infected with Hepatitis B and C viruses are several times more than those infected with HIV. (d) Some of those infected with Hepatitis B and C viruses do not show the symptoms for many years. |
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