Innovations in Biotechnology and Medical Sciences

Miller-Urey Hypothesis

Note4Students

From UPSC perspective, the following things are important :

Prelims level: Miller-Urey Hypothesis

Why in the News?

A recent study led by Stanford University chemist Richard Zare has introduced a novel perspective on the origins of life on Earth, providing an alternative to the well-known Miller-Urey hypothesis.

Miller-Urey Hypothesis

About the Miller-Urey Hypothesis

  • The Miller-Urey hypothesis emerged from an experiment conducted in 1952 by chemists Stanley Miller and Harold Urey.
    • It sought to simulate the conditions of early Earth to understand how life could have originated.
  • They used a mixture of water, methane, ammonia, and hydrogen, gases believed to be present in the early Earth’s atmosphere.
  • The setup also included an electric spark to simulate lightning, which they hypothesized could have played a role in the formation of organic compounds.
  • Results: The experiment successfully demonstrated that organic molecules, like amino acids, essential for life, could form when an electrical spark (simulating lightning) was applied to the gas mixture.
  • Impact and Debate:
    • The experiment was a landmark in understanding life’s chemical origins.
    • However, over time, critics argued that real lightning would have been rare and mostly occurred over open ocean, where organic compounds would have been quickly dispersed.
    • This led to the questioning of lightning as the primary trigger for life’s origins.

Life on Earth and the Role of ‘Microlightning’ in Water Droplets

  • The Stanford study shows that when water droplets divide, they develop opposing electrical charges—larger droplets become positively charged, and smaller droplets become negatively charged.
  • When these oppositely charged droplets come close together, tiny sparks (termed micro-lightning) can leap between them, mimicking the electrical phenomena that occur in thunderstorms.
  • Experimental Evidence:
    • In the experiment, when water sprays were mixed with nitrogen, methane, carbon dioxide, and ammonia, they produced organic compounds like glycine and uracil, similar to those in the Miller-Urey experiment.
    • Microlightning from water sprays can therefore generate organic compounds, providing a plausible and common natural process for the origin of life.
  • These microlightning events could have been far more common and accessible than lightning strikes, offering an alternative mechanism for the generation of life-building organic molecules.

PYQ:


[UPSC 2012] Which one of the following sets of elements was primarily responsible for the origin of life on the Earth?

(a) Hydrogen, Oxygen, Sodium

(b) Carbon, Hydrogen, Nitrogen

(c) Oxygen, Calcium, Phosphorus

(d) Carbon, Sodium, Phosphorus

 

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