From UPSC perspective, the following things are important :
Prelims level: OptiDrop, C-MAP, Cytometry
Mains level: NA
Why in the news?
The Centre for Cellular and Molecular Platforms (C-CAMP) in Bengaluru has unveiled OptiDrop platform designed to simplify and significantly reduce the cost of studying single cells.
About C-CAMP
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What is OptiDrop?
- OptiDrop presents a cost-effective alternative to traditional flow cytometry methods, making single-cell analysis more accessible to a broader range of researchers and institutions.
- OptiDrop simplifies single-cell analysis by encapsulating individual cells within droplets, facilitating easier manipulation and analysis compared to traditional methods.
- Key features such as affordability, live data visualization, compact design, and closed-system architecture enhance its suitability for diverse clinical applications.
| Cytometry is the measurement of number and characteristics of cells. Variables that can be measured by cytometric methods include cell size, cell count, cell morphology (shape and structure), cell cycle phase, DNA content, and the existence or absence of specific proteins on the cell surface or in the cytoplasm. |
Applications of OptiDrop
- Expansive Utility: OptiDrop unlocks various downstream applications, including drug screening, environmental monitoring, immunotherapy, and single-cell genomics, revolutionizing research across multiple domains.
- Advanced Research Capabilities: Researchers can leverage OptiDrop to study individual cell behavior during drug screenings, identify and monitor environmental contaminants, sort specialized cell populations, and explore genetic heterogeneity within cell populations.
Benefits offered by OptiDrop
- Accessible Technology: Unlike conventional cytometers, which can cost up to Rs 40 lakh or more, OptiDrop offers a cost-efficient solution likely priced around Rs 10 lakh, making it accessible to a broader range of research labs and institutions.
- Affordable Scalability: OptiDrop’s affordable pricing and scalable design allow institutions of varying sizes to adopt the technology, democratizing access to cutting-edge single-cell analysis capabilities.
- Long-Term Sustainability: By reducing the barrier to entry for single-cell analysis, OptiDrop paves the way for sustainable and impactful research initiatives, driving innovation and discovery in the life sciences.
PYQ:2020: Which of the following statements are correct regarding the general difference between plant and animal-calls? 1. Plant cells have cellulose cell walls whilst animal cells do not. 2. Plant cells do not have plasma membrane unlike animal cells which do. 3. Mature plant cell has one large vacuole whilst animal cell has many small vacuoles. Select the correct answer using the code given below: (a) 1 and 2 only (b) 2 and 3 only (c) 1 and 3 only (d) 1, 2 and 3
Practice MCQ:The OptiDrop equipment recently seen in news finds application in: (a) Cytometry (b) Astronomy (c) Geology (d) Radiometry |
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