Note4Students
From UPSC perspective, the following things are important :
Prelims level: Combination Therapeutic Clotting Implant
Why in the News?
Scientists at the Institute of Nano Science and Technology (INST), Mohali, in collaboration with other researchers have developed the Combination Therapeutic Clotting Implant.
What is the Combination Therapeutic Clotting Implant?
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How does It Work?
- The implant is created using Nano-Micro-Sera (NMS), which consists of drug and metal-based nanomedicine stabilized by the patient’s own serum protein corona.
- The hybrid implant is reinforced into autologous fibrin, which quickly bonds with damaged tissue in the tumor bed after surgery.
- Once the surgical site is closed, the implant delivers localized chemo-phototherapy, triggering immunogenic cell death (ICD).
- This process activates dendritic cells and T-cells, which boosts the body’s immune response and prevents the recurrence of tumors.
Significance of the Implant
- The implant offers an affordable and effective solution for localized post-surgical cancer management, especially for marginalized patients.
- By using the patient’s own serum proteins and fibrin, the implant ensures personalized treatment, reducing the risk of systemic toxicity.
- The implant’s design is resource-efficient, making it accessible for bedside fabrication with simple equipment, ensuring wider availability.
- It has demonstrated superior outcomes in suppressing recurrent breast tumors, and its use could prevent tumor recurrence and reducing the chances of metastasis.
PYQ:[2015] With reference to the use of nanotechnology in health sector, which of the following statements is/are correct? 1. Targeted drug delivery is made possible by nanotechnology. 2. Nanotechnology can largely contribute to gene therapy. Select the correct answer using the codes given below: (a) 1 only (b) 2 only (c) Both 1 and 2 (d) Neither 1 nor 2 |
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