Health Sector – UHC, National Health Policy, Family Planning, Health Insurance, etc.

The grave threat from AMR

Note4Students

From UPSC perspective, the following things are important :

Prelims level: Antimicrobial resistance;

Mains level: Reason behind the AMR Increasing;

Why in the News?

Ahead of the UN General Assembly High-Level Meeting on antimicrobial resistance, WHO published its first-ever guidance on Antibiotic pollution from manufacturing.

Common Pathogens Found in India

The three most common pathogens associated with antimicrobial resistance (AMR) in India, as reported by the Indian Council of Medical Research (ICMR), are:

  • Escherichia coli (E. coli): Known for causing gut infections, E. coli has shown a significant decrease in susceptibility to antibiotics, particularly carbapenems, from 81.4% in 2017 to 62.7% in 2023.
  • Klebsiella pneumoniae: This pathogen can lead to pneumonia and urinary tract infections. Its susceptibility to carbapenem-class antibiotics has also declined, with rates dropping from 58.5% to 35.6% and from 48% to 37.6% between 2017 and 2023.
  • Acinetobacter baumannii: Primarily associated with hospital-acquired infections, this pathogen has a high resistance rate to carbapenems, standing at 88% in 2023.

What is Antimicrobial Resistance (AMR) and Why is it a Cause for Concern?

  • Antimicrobial resistance (AMR) occurs when pathogens evolve to survive despite the presence of antimicrobial drugs, rendering standard treatments ineffective. This situation arises mainly due to the misuse and overuse of antibiotics, leading to the development of resistant strains or “superbugs.” 
  • According to the WHO, emergence and spread of AMR could significantly undermine the effectiveness of antibiotics globally, impacting healthcare outcomes, especially for patients with multiple diseases.

Why is AMR Increasing?

Several factors contribute to the increasing rates of AMR in India:

  • Self-medication: Many individuals self-prescribe antibiotics for conditions like fever without proper medical consultation, often for viral infections where antibiotics are ineffective.
  • Prescribing habits: A significant percentage of antibiotics are prescribed not for treating infections but for prevention. Doctors often resort to broad-spectrum antibiotics without conducting necessary diagnostic tests, leading to inappropriate usage.
  • Lack of regulation: The management of pharmaceutical waste from antibiotic manufacturing is largely unregulated, contributing to environmental pollution and the spread of resistant bacteria.

What needs to be done?

  • Prevention of Infections: Implementing better hygiene practices, improving sanitation, and promoting vaccinations can help reduce the incidence of infections, thereby decreasing the reliance on antibiotics.
  • Education for Healthcare Providers: Train doctors to prescribe antibiotics judiciously, reserve stronger antibiotics for hospital patients, and emphasise the importance of diagnostic testing, which can help ensure appropriate antibiotic use.
  • Regulatory Improvements: Strengthening regulations around antibiotic manufacturing and waste management is crucial for controlling antibiotic pollution and preventing the emergence of resistant strains.

Mains PYQ:

Q Can overuse and free availability of antibiotics without Doctor’s prescription, be contributors to the emergence of drug-resistant diseases in India? What are the available mechanisms for monitoring and control? Critically discuss the various issues involved.  (UPSC IAS/2016)

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