Coronavirus – Disease, Medical Sciences Involved & Preventive Measures

What is Human Metapneumo- Virus (HMPV)?

Note4Students

From UPSC perspective, the following things are important :

Prelims level: HMPV and its causes

Why in the News?

Human Metapneumovirus (HMPV) has recently become a topic of widespread discussion in India, fueled by sensational media reports. These reports claim the emergence of a “new dangerous virusfrom China, leading to unnecessary public panic and misinformation.

What is Human Metapneumovirus (HMPV)?

  • Human Metapneumovirus (HMPV) is a respiratory virus that primarily causes mild to moderate respiratory infections.
  • It belongs to the Paramyxoviridae family, the same group of viruses that includes respiratory syncytial virus (RSV) and parainfluenza.
  • HMPV was first identified in 2001 and has been circulating globally for decades.
  • Most infections are mild and self-limiting, but HMPV can cause severe illness in vulnerable groups such as:
    • Elderly individuals.
    • Young children (especially under five years).
    • Immunocompromised individuals or those with chronic illnesses.
  • Transmission:
    • Spread primarily through respiratory droplets, direct contact with contaminated surfaces, or close contact with infected individuals.
  • Diagnosis:
    • Advanced PCR-based respiratory panels can detect HMPV. However, these tests are not routinely performed unless required in vulnerable patients or during hospital outbreaks.

Symptoms and Treatment for HMPV:

  • HMPV symptoms overlap with those of other respiratory viruses like influenza and RSV.
  • Mild Symptoms: Runny nose; Sore throat; Cough; Fever; Fatigue.
  • Severe Symptoms (in vulnerable populations): Bronchitis; Wheezing; Pneumonia; Difficulty breathing; Hypoxia in extreme cases.
  • No Specific Antiviral or Vaccine: Unlike flu and RSV, there is no targeted antiviral therapy or vaccine for HMPV.
  • Supportive Care: Rest and hydration; Over-the-counter medications to manage fever and pain (e.g., acetaminophen or ibuprofen).
  • For Severe Cases: Hospitalization may be required for oxygen therapy, nebulization, or other supportive measures.

Present Scenario- Global and National:

  • HMPV is one of the leading causes of respiratory infections worldwide, following influenza and RSV.
  • Studies indicate HMPV accounts for 5-10% of respiratory infections in children and vulnerable adults annually.
  • The Indian Council of Medical Research (ICMR) recently reported two HMPV cases in Karnataka involving babies with a history of bronchopneumonia.
  • These are the first cases identified using PCR diagnostic tools after a surge in HMPV cases in China.

PYQ:

[2022] In the context of vaccines manufactured to prevent COVID-19 pandemic, consider the following statements:

1. The Serum Institute of India produced COVID-19 vaccine named Covishield using mRNA platform.

2. Sputnik V vaccine is manufactured using a vector-based platform.

3. COVAXIN is an inactivated pathogen-based vaccine.

Which of the statements given above are correct?

(a) 1 and 2 only

(b) 2 and 3 only

(c) 1 and 3 only

(d) 1, 2 and 3

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