Note4Students
From UPSC perspective, the following things are important :
Prelims level: Molnupiravir
Mains level: Vaccine for covid
A new drug called Molnupiravir has been shown to stop the transmission of SARS-CoV-2 in 24 hours.
Must read:
What is mRNA vaccine?
Molnupiravir
- Molnupiravir is an experimental antiviral drug which is orally active and was developed for the treatment of influenza.
- It is a drug of the synthetic nucleoside derivative N4-hydroxycytidine, and exerts its antiviral action through introduction of copying errors during viral RNA replication.
- Molnupiravir is being developed by the biotechnology firm Ridgeback Biotherapeutics in collaboration with pharmaceutical firm Merck.
- The research team repurposed MK-4482/EIDD-2801 against SARS-CoV-2 and tested it on ferrets.
- This is the first demonstration of an orally available drug to rapidly block SARS-CoV-2 transmission and it can be a game-changer.
Get an IAS/IPS ranker as your 1: 1 personal mentor for UPSC 2024
Attend Now
Note4Students
From UPSC perspective, the following things are important :
Prelims level: Tharu tribals
Mains level: Tourism development in tribal circuits
The Uttar Pradesh government has recently embarked upon a scheme to take the unique culture of its ethnic Tharu tribe across the world.
The Terai or Tarai is a lowland region in northern India and southern Nepal that lies south of the outer foothills of the Himalayas, the Sivalik Hills, and north of the Indo-Gangetic Plain. This lowland belt is characterized by tall grasslands, scrub savannah, sal forests and clay rich swamps.
Tharu Tribals
- The community belongs to the Terai lowlands, amid the Shivaliks of lower Himalayas. Most of them are forest dwellers and some practised agriculture.
- The word Tharu is believed to be derived from their, meaning followers of Theravada Buddhism.
- The Tharus live in both India and Nepal. In the Indian Terai, they live mostly in Uttarakhand, Uttar Pradesh, and Bihar.
- According to the 2011 census, the Scheduled Tribe population in Uttar Pradesh was more than 11 lakh; this number is estimated to have crossed 20 lakh now.
- The biggest chunk of this tribal population is made up of Tharus.
- Members of the tribe survive on wheat, corn and vegetables are grown close to their homes. A majority still lives off the forest.
Tharu language, food, and culture
- They speak various dialects of Tharu, a language of the Indo-Aryan subgroup, and variants of Hindi, Urdu, and Awadhi.
- In central Nepal, they speak a variant of Bhojpuri, while in eastern Nepal, they speak a variant of Maithili.
- Tharus worship Lord Shiva as Mahadev and call their supreme being “Narayan”, who they believe is the provider of sunshine, rain, and harvests.
- Tharu women have stronger property rights than is allowed to women in mainstream North Indian Hindu custom.
- Standard items on the Tharu plate are bagiya or dhikri – which is a steamed dish of rice flour that is eaten with chutney or curry – and ghonghi, an edible snail that is cooked in a curry made of coriander, chili, garlic, and onion.
What is this scheme about?
- The UP government is working to connect Tharu villages in the districts of Balrampur, Bahraich, Lakhimpur and Pilibhit bordering Nepal, with the homestay scheme of the UP Forest Department.
- The idea is to offer tourists an experience of living in the natural Tharu habitat, in traditional huts made of grass collected mainly from the forests.
- Tharu homeowners will be able to charge tourists directly for the accommodation and home-cooked meals.
- The government expects both domestic and international tourists to avail of the opportunity to obtain a taste of the special Tharu culture by staying with them, observing their lifestyle, food habits, and attire.
Get an IAS/IPS ranker as your 1: 1 personal mentor for UPSC 2024
Attend Now
Note4Students
From UPSC perspective, the following things are important :
Prelims level: Havana syndrome
Mains level: Threats of microwave warfare
Nearly four years after a mysterious neurological illness started to affect American diplomats in Cuba, China, and other countries, a report has found “directed” microwave radiation to be its “plausible” cause.
Q.Microwave warfare is the new nuke. Discuss.
The ‘Havana syndrome’
- In late 2016, US diplomats in Havana reported feeling ill after hearing strange sounds and experiencing odd physical sensations in their hotel rooms or homes.
- The symptoms included nausea, severe headaches, fatigue, dizziness, sleep problems, and hearing loss, which have since come to be known as “Havana Syndrome”.
- Cuba had denied any knowledge of the illnesses even though the US had accused it of carrying out “sonic attacks”, leading to an increase in tensions.
Possible factor: Microwave Weapons
- “Microwave weapons” are supposed to be a type of direct energy weapons, which aim highly focused energy in the form of sonic, laser, or microwaves, at a target.
- People exposed to high-intensity microwave pulses have reported a clicking or buzzing sound as if seeming to be coming from within your head.
- It can have both acute and long-term effects — without leaving signs of physical damage.
- These weapons are considered to be the cause of the “syndrome” whose symptoms include nausea, dizziness, fatigue, and cognitive difficulties.
How did researchers deduce that?
- The researchers have examined four possibilities to explain the symptoms — infection, chemicals, psychological factors and microwave energy.
- The experts examined the symptoms of about 40 government employees.
- The report concluded that directed pulsed RF (radio frequency) energy appears to be the most plausible mechanism in explaining these cases among those that the committee considered.
Get an IAS/IPS ranker as your 1: 1 personal mentor for UPSC 2024
Attend Now
Note4Students
From UPSC perspective, the following things are important :
Prelims level: GI tags in news
Mains level: Importance of GI tags
The Himachal Pradesh government is trying to obtain GIs for five products from the state – Karsog Kulth, Thangi of Pangi, Chamba Metal Crafts, Chamba Chukh, and Rajmah of Bharmour.
Read more about GIs at:
GI(Geographical Indicator) Tags
Which are the five HP products?
- Karsog Kulth: Kulthi or Kulth (horse gram) is a legume grown as a kharif crop in Himachal Pradesh. Kulth grown in the Karsog area of Mandi district is believed to be particularly rich in amino acids.
- Pangi ki Thangi: It is a type of hazelnut which grows in Pangi valley located in the northwestern edge of Himachal. It is known for its unique flavour and sweetness.
- Chamba metal crafts: These include items such as metal idols and brass utensils which, historically, were made by skilled artisans in the courts of kings of Chamba. There are efforts to revive the trade, and a plate made from a brass-like alloy and having carvings of gods and goddesses is still popular.
- Chamba Chukh: It’s a chutney made from green and red chillies grown in Chamba, and prepared in traditional and unique ways. The practice has largely declined in rural households of Chamba, but survives to some extent at the small-scale industrial level.
- Bharmouri Rajmah: It’s more specifically called the Kugtalu Rajmah, since it grows in the area around Kugti Pass in the Bharmour region of Chamba district. It is rich in proteins and has a unique flavor.
How many registered GIs does Himachal currently have?
- They are eight in number.
- It includes four handicrafts (Kullu Shawl, Chamba Rumal, Kinnauri Shawl and Kangra Paintings).
- There are three agricultural products (Kangra Tea, Basmati and Himachali Kala Zeera) and one manufactured product (Himachali Chulli Oil).
- Kullu Shawl and Kangra Tea were the first to be registered in 2005-06.
- Basmati has been registered jointly from seven states of North India, including Himachal Pradesh.
- Chulli (apricot) oil and kala jeera (cumin), mainly associated with Kinnaur and known for their medicinal properties, were the last to be registered in 2018-19.
How does a GI tag help?
- A GI tag provides a better market for these products and prevents misuse of the name.
- A GI registration is given to an area, not a trader, but once a product gets the registration, traders dealing in the product can apply for selling it with the GI logo.
- Authorised traders are each assigned a unique GI number. For example, Kullu shawl has 135 authorised traders. A shawl made in Ludhiana cannot be sold as a Kullu shawl.
- If any unauthorised trader, even from Kullu, tries to sell a shawl under the name of Kullu shawl, he or she can be prosecuted under The Geographical Indications of Goods (Registration and Protection) Act, 1999.
- GIs are also expected to boost or revive the items whose production has declined, as is being aimed in the case of Chamba Chukh and metal crafts.
Back2Basics: Geographical Indication (GI)
- The World Intellectual Property Organisation defines a GI as “a sign used on products that have a specific geographical origin and possess qualities or a reputation that are due to that origin”.
- GIs are typically used for agricultural products, foodstuffs, handicrafts, industrial products, wines and spirit drinks.
- Internationally, GIs are covered as an element of intellectual property rights under the Paris Convention for the Protection of Industrial Property.
- They are also covered under the Trade Related Aspects of Intellectual Property Rights (TRIPS) Agreement.
- Presently, there are 370 registered GIs in India.
Get an IAS/IPS ranker as your 1: 1 personal mentor for UPSC 2024
Attend Now
Note4Students
From UPSC perspective, the following things are important :
Prelims level: Red Sea Turtles
Mains level: Impact of climate changes
Turtle populations in the Red Sea could be turning overwhelmingly female because of a rise in sea temperatures caused due to anthropogenic climate change, a new study has showed.
Try this PYQ:
Q.Consider the following fauna of India:
- Gharial
- Leatherback turtle
- Swamp deer
Which of the above is/are endangered?
(a) 1 and 2 only
(b) 3 only
(c) 1, 2 and 3
(d) None
Red Sea Turtles
- There are seven extant species worldwide, five of which can be found in the Red Sea: the green turtle, the hawksbill turtle, the loggerhead turtle, the olive ridley turtle and the leatherback turtle.
- In order to maintain a 50:50 ratio of male and female in the population, a temperature of 29.2 degrees Celsius is pivotal.
- Above this, hatchlings would be predominantly female.
- The sand temperatures at four of the sites exceeded 29.2 degrees; leading the team to the conclusion that ‘feminization’ of the population could be already happening.
Their significance
- Marine turtles—as all top predators—have a prominent role in maintaining balanced and healthy ecosystems, in particular seagrass beds and coral reefs.
- They also help in transporting nutrients towards naturally nutrient-poor ecosystems (the nesting beaches), and providing food and transportation for other marine species (e.g., barnacles and commensal crabs).
- Marine turtles also play an important role in the economy of the tourism industry.
Get an IAS/IPS ranker as your 1: 1 personal mentor for UPSC 2024
Attend Now
Note4Students
From UPSC perspective, the following things are important :
Prelims level: HL-2M Tokamak, Nuclear fusion and fission
Mains level: Artificial Sun
China successfully powered up its “artificial sun” nuclear fusion reactor for the first time marking a great advance in the country’s nuclear power research capabilities.
Scratch your school basics to answer this PYQ:
Q.The known forces of nature can be divided into four classes, viz, gravity, electromagnetism, weak nuclear force and strong nuclear force.
With reference to them, which one of the following statements is not correct? (CSP 2012)
(a) Gravity is the strongest of the four
(b) Electromagnetism act only on particles with an electric charge
(c) Weak nuclear force causes radioactivity
(d) Strong nuclear force holds protons and neutrons inside the nuclear of an atom.
HL-2M Tokamak
- The HL-2M Tokamak reactor is China’s largest and most advanced nuclear fusion experimental research device.
- The mission is named Experimental Advanced Superconducting Tokamak (EAST).
- Located in Sichuan province and completed late last year, the reactor is often called an “artificial sun” on account of the enormous heat and power it produces.
- It uses a powerful magnetic field to fuse hot plasma and can reach temperatures of over 150 million degrees Celsius- approximately ten times hotter than the core of the sun.
- Scientists hope that the device can potentially unlock a powerful clean energy source.
Back2Basics: Nuclear Fusion
- Nuclear fusion is a reaction in which two or more atomic nuclei are combined to form one or more different atomic nuclei and subatomic particles (neutrons or protons).
- Fusion is the process by which the sun and other stars generate light and heat. It is a nuclear process, where energy is produced by smashing together light atoms.
- It is the opposite reaction of fission, where heavy elements like Uranium and Thorium are split apart.
Nuclear Fusion Reaction
- For a nuclear fusion reaction to occur, it is necessary to bring two nuclei so close that nuclear forces become active and glue the nuclei together.
- Nuclear forces are small-distance forces and have to act against the electrostatic forces where positively charged nuclei repel each other.
- This is the reason nuclear fusion reactions occur mostly in high density, high-temperature environment (millions of degree Celsius) which is practically very difficult to achieve under laboratory conditions.
Get an IAS/IPS ranker as your 1: 1 personal mentor for UPSC 2024
Attend Now
Note4Students
From UPSC perspective, the following things are important :
Prelims level: Surveyor-2
Mains level: Not Much
NASA has confirmed that the Near-Earth Object called 2020 SO is the rocket booster that helped lift the space agency’s Surveyor spacecraft toward the Moon in 1966.
Try this PYQ:
Consider the following phenomena:
- Size of the sun at dusk
- Colour of the sun at dawn
- Moon being visible at dawn
- Twinkle of stars in the sky
- Polestar being visible in the sky
Which of the above are optical illusions?
(a) 1, 2 and 3
(b) 3, 4 and 5
(c) 1, 2 and 4
(d) 2, 3 and 5
What is Surveyor-2?
- The Surveyor-2 spacecraft was supposed to make a soft landing on the Moon’s surface in September 1966, during which time one of the three thrusters failed to ignite.
- As a result of this the spacecraft started spinning and crashed on the surface.
- The aim of the mission was to reconnoiter the lunar surface ahead of the Apollo missions that led to the first lunar landing in 1969.
- While the spacecraft crashed into the Moon’s surface, the rocket booster disappeared into an unknown orbit around the Sun.
How was the object determined to be the rocket booster?
- Astronomers track asteroids using telescope to determine if there are potentially hazardous asteroids that pose a threat to the planet.
- Therefore, it is also important for them to be able to distinguish between natural and artificial objects that orbit around the Sun.
- The rocket booster has come “somewhat close” to the Earth in the past few decades.
- One approach to the Earth in late 1966 was so close that the object was thought to have originated from Earth.
- In September, the NASA-funded telescope detected it.
Get an IAS/IPS ranker as your 1: 1 personal mentor for UPSC 2024
Attend Now
Note4Students
From UPSC perspective, the following things are important :
Prelims level: Arecibo Radio Telescope
Mains level: Not Much
A massive radio telescope at Puerto Rico’s Arecibo Observatory — one of the world’s largest — collapsed on after sustaining severe damage, following 57 years of astronomical discoveries.
Try this PYQ:
Which of the following is/are cited by the scientists as evidence/evidence for the continued expansion of the universe?
- Detection of microwaves in space
- Observation of redshirt phenomenon in space
- Movement of asteroids in space
- Occurrence of supernova explosions in space
Codes:
(a) 1 and 2 only
(b) 2 only
(c) 1, 3 and 4
(d) None of the above can be cited as evidence.
Arecibo Telescope
- The Arecibo Observatory, also known as the National Astronomy and Ionosphere Center (NAIC), was an observatory in Arecibo, Puerto Rico owned by the US National Science Foundation (NSF).
- It was the world’s largest single-aperture telescope for 53 years, surpassed in July 2016 by the Five-hundred-meter Aperture Spherical Telescope (FAST) in China.
- The second-largest single-dish radio telescope in the world, it had withstood many hurricanes and earthquakes since it was first built in 1963.
Its contributions
- Being the most powerful radar, scientists employed Arecibo to observe planets, asteroids and the ionosphere.
- It made several discoveries over the decades, including finding prebiotic molecules in distant galaxies, the first exoplanets, and the first millisecond pulsar.
- In 1967, Arecibo was able to discover that the planet Mercury rotates in 59 days and not 88 days as had been originally thought.
- In the following decades, it also served as a hub in the search for extraterrestrial life, and would look for radio signals from alien civilizations.
- In 1993, scientists Russell Hulse and Joseph Taylor were awarded the Nobel Prize in Physics for their work on the observatory in monitoring a binary pulsar.
- It provided a strict test of Einstein’s Theory of General Relativity and the first evidence for the existence of gravitational waves.
Get an IAS/IPS ranker as your 1: 1 personal mentor for UPSC 2024
Attend Now
Note4Students
From UPSC perspective, the following things are important :
Prelims level: ASKAP telescope
Mains level: Not Much
A powerful new telescope ASKAP, in Australia has mapped vast areas of the universe in record-breaking time, revealing a million new galaxies and opening the way to new discoveries.
Note all important telescopes in news and their features. Some of them are – Thirty Meter Telescope, Giant Metrewave Radio Telescope, Spitzer, Chandra etc.
What is ASKAP?
- ASKAP is a telescope designed over a decade ago and located about 800 km north of Perth.
- It became fully operational in February 2019 and is currently conducting pilot surveys of the sky before it can begin large-scale projects from 2021 onward.
- ASKAP surveys are designed to map the structure and evolution of the Universe, which it does by observing galaxies and the hydrogen gas that they contain.
- One of its most important features is its wide field of view, because of which it has been able to take panoramic pictures of the sky in great detail.
- The telescope uses novel technology developed by CSIRO- the Australian space agency, which is a kind of a “radio camera” to achieve high survey speeds and consists of 36 dish antennas, which are each 12m in diameter.
- The survey team has been able to observe over 83 per cent of the sky visible from ASKAP’s site in Western Australia.
Significance of the results
- The present Rapid ASKAP Continuum Survey (RACS) taken by the ASKAP telescope is like a “Google map” of the Universe.
- Mapping the Universe on such a scale enables astronomers to study the formation of stars and how galaxies and their supermassive black holes evolve and interact with each other.
- Significantly, the images the telescope has taken are on average deeper and have better spatial resolution compared to those taken during other surveys of the sky.
- The aim of the RACS survey is to generate images that will aid future surveys undertaken using the telescope.
Get an IAS/IPS ranker as your 1: 1 personal mentor for UPSC 2024
Attend Now
Note4Students
From UPSC perspective, the following things are important :
Prelims level: Not Much
Mains level: Women in Judiciary
Attorney-General has told the Supreme Court that more women judges in constitutional courts would certainly improve gender sensitivity in the judiciary.
Q.Women judges could bring a more comprehensive and empathetic perspective of gender sensitivity in the judiciary. Discuss.
Women in Judiciary: A dismal figure
- The Supreme Court has only two women judges as against a sanctioned strength of 34 judges.
- There has never been a female Chief Justice. This figure is consistently low across the higher judiciary.
- There are only 80 women judges out of the sanctioned strength of 1,113 judges in the High Courts and the Supreme Court.
- Only two of these 80 women judges are in the Supreme Court and the other 78 are in various High Courts, comprising only 7.2% of the number of judges.
- There are six High Courts — Manipur, Meghalaya, Patna, Tripura, Telangana, and Uttarakhand — where there are no sitting women judges.
A short timeline
- The first female Judge appointed in Supreme Court was Justice M. Fathima Beevi from Kerala in 1987.
- She was later followed by Justice Sujata V. Manohar from Maharashtra in 1994 and in the year 2000, Justice Ruma Pal was appointed from West Bengal.
- And in the year 2010, Justice Gyan Sudha Misra from Bihar was appointed.
- In 2014, Justice Ranjana Desai from Mumbai was appointed and currently, Justice R. Banumathi from Tamil Nadu is the only woman judge in Supreme Court.
(Note: This data might be useful for State PSCs or other exams. UPSC aspirants need not remember this.)
What did the A-G say?
- Improving the representation of women could go a long way towards a more balanced and empathetic approach in cases involving sexual violence.
- Judges need to be trained to place themselves in the shoes of the victim of sexual violence while passing orders, said the AG.
- There is a dearth of compulsory courses in gender sensitization in law schools.
- Certain law schools have the subject either as a specialization or as an elective.
Why need more women in Judiciary?
- The entry of women judges into spaces from which they had historically been excluded has been a positive step in the direction of judiciaries being perceived as being more transparent, inclusive, and representative.
- By their mere presence, women judges enhance the legitimacy of courts, sending a powerful signal that they are open and accessible to those who seek recourse to justice.
- They could contribute far more to justice than improving its appearance: they also contribute significantly to the quality of decision-making, and thus to the quality of justice itself.
- Women judges bring those lived experiences to their judicial actions, experiences that tend toward a more comprehensive and empathetic perspective.
- By elucidating how laws and rulings can be based on gender stereotypes, or how they might have a different impact on women and men, a gender perspective enhances the fairness of the adjudication.
Get an IAS/IPS ranker as your 1: 1 personal mentor for UPSC 2024
Attend Now
Note4Students
From UPSC perspective, the following things are important :
Prelims level: E-Sanjeevani
Mains level: Telemedicine and its effectiveness
In a landmark achievement, eSanjeevani, Health Ministry’s national telemedicine initiative today completed 9 lakh consultations.
Although telemedicine brings with it many benefits, there are some downsides to it as well. Discuss.
What is E-Sanjeevani?
- Ministry of Health & Family Welfare has launched two variants of eSanjeevani namely – doctor to doctor (eSanjeevani AB-HWC) in the hub and spoke model and patient to doctor (eSanjeevaniOPD).
- E-Sanjeevani OPD (out-patient department) is a telemedicine variant for the public to seek health services remotely; it was rolled out on 13th of April 2020 during the first lockdown in the country.
- It enables virtual meetings between the patients and doctors & specialists from geographically dispersed locations, through video conferencing that occurs in real-time.
- At the end of these remote consultations, eSanjeevani generates electronic prescriptions which can be used for sourcing medicines.
- Andhra Pradesh was the first state to roll out eSanjeevani AB-HWC services in November 2019.
Benefits of telemedicine
Telemedicine benefits patients in the following ways:
- Transportation: Patients can avoid spending gas money or wasting time in traffic with video consultations.
- No missing work: Today, individuals can schedule a consultation during a work break or even after work hours.
- Childcare/Eldercare Challenges: Those who struggle to find care options can use telemedicine solutions.
Get an IAS/IPS ranker as your 1: 1 personal mentor for UPSC 2024
Attend Now
Note4Students
From UPSC perspective, the following things are important :
Prelims level: MSP calculation
Mains level: Fixation of MSP and its legal backing
Talks between farmer unions and the government failed to reach a resolution. The main bone of contention in these talks is the Minimum Support Price (MSP) for crops, which farmers fear the new laws will do away.
Try this:
Q.There is also a point of view that agriculture produce market committees (APMCs) set up under the state acts have not only impeded the development of agriculture but also have been the cause of food inflation in India. Critically examine. (CSM 2014)
What is MSP?
- The MSP assures the farmers of a fixed price for their crops, well above their production costs.
- MSP, by contrast, is devoid of any legal backing. Access to it, unlike subsidised grains through the PDS, isn’t an entitlement for farmers.
- They cannot demand it as a matter of right. It is only a government policy that is part of administrative decision-making.
- The Centre currently fixes MSPs for 23 farm commodities based on the Commission for Agricultural Costs and Prices (CACP) recommendations.
Why in news yet again?
- The Union Budget for 2018-19 had announced that MSP would be kept at levels of one and half times of the cost of production.
- This year the govt. has increased the MSP for all mandated Kharif, Rabi and other commercial crops with a return of at least 50 per cent of the cost of production for the agricultural year 2018-19 and 2019-20.
- This is the ambiguity from where this 1.5 times formula arrived at.
How did the government fix the MSPs of crops before every planting season?
- The CACP considered various factors while recommending the MSP for a commodity, including the cost of cultivation.
- It also takes into account the supply and demand situation for the commodity; market price trends (domestic and global) and parity vis-à-vis other crops; and implications for consumers (inflation), environment (soil and water use) and terms of trade between agriculture and non-agriculture sectors.
What changed with the 2018 budget?
- The Budget for 2018-19 announced that MSPs would henceforth be fixed at 1.5 times of the production costs for crops as a “pre-determined principle”.
- Simply put, the CACP’s job now was only to estimate production costs for a season and recommend the MSPs by applying the 1.5-times formula.
How was this production cost arrived at?
- The CACP projects three kinds of production cost for every crop, both at the state and all-India average levels.
- ‘A2’ covers all paid-out costs directly incurred by the farmer — in cash and kind — on seeds, fertilisers, pesticides, hired labour, leased-in land, fuel, irrigation, etc.
- ‘A2+FL’ includes A2 plus an imputed value of unpaid family labour.
- ‘C2’ is a more comprehensive cost that factors in rentals and interest forgone on owned land and fixed capital assets, on top of A2+FL.
Now try this PYQ:
Q.The economic cost of food grains to the Food Corporation of India is Minimum Support Price and bonus (if any) paid to the farmers plus:
(a) Transportation cost only
(b) Interest cost only
(c) Procurement incidentals and distribution cost
(d) Procurement incidentals and charges for godowns
Which production costs were taken in fixing the MSPs?
- In 2018, then FM Arun Jaitley’s did not specify the cost on which the 1.5-times formula was to be computed.
- But the CACP’s ‘Price Policy for Kharif Crops: The Marketing Season 2018-19’ report stated that its MSP recommendation was based on 1.5 times the A2+FL costs.
What are the farmer’s demands?
- Farm activists, however, had said that the 1.5-times MSP formula should have been applied on the C2 costs.
- CACP considers A2+FL and C2 costs, both while recommending MSP. It reckons only A2+FL cost for return.
- However, C2 costs are used by CACP primarily as benchmark reference costs (opportunity costs) to see if the MSPs recommended by them at least cover these costs in some of the major producing States.
Get an IAS/IPS ranker as your 1: 1 personal mentor for UPSC 2024
Attend Now
Note4Students
From UPSC perspective, the following things are important :
Prelims level: Vaccine for COVID
Mains level: Universalization of vaccines and associated challenges in India
The US drugmaker Moderna said it was applying for emergency use authorisation for its vaccine in India.
Practice question for Mains:
Q. What is Vaccine Nationalism? Discuss various ethical issues involved and its impact on vulnerable populations across the globe.
Emergency Use Authorisation (EUA)
- Vaccines and medicines, and even diagnostic tests and medical devices, require the approval of a regulatory authority before they can be administered.
- In India, the regulatory authority is the Central Drugs Standard Control Organisation (CDSCO).
- The approval is granted after an assessment of their safety and effectiveness, based on data from trials. In fact, approval from the regulator is required at every stage of these trials.
- This is a long process, designed to ensure that medicine or vaccine is absolutely safe and effective.
- The fastest approval for any vaccine until now — the mumps vaccine in the 1960s — took about four-and-a-half years after it was developed.
Exceptions for emergency
- In emergency situations, like the current one, regulatory authorities around the world have developed mechanisms to grant interim approvals.
- However, there should sufficient evidence to suggest a medical product is safe and effective.
- Final approval is granted only after completion of the trials and analysis of full data; until then, EUA allows the medicine or the vaccine to be used on the public.
What is the process of getting a EUA in India?
- India’s drug regulations do not have provisions for a EUA, and the process for receiving one is not clearly defined or consistent.
- Despite this, CDSCO has been granting emergency or restricted emergency approvals to Covid-19 drugs during this pandemic — for remdesivir and favipiravir in June, and itolizumab in July.
Associated risks
- The public has to be informed that a product has only been granted a EUA and not full approval.
- In the case of a Covid-19 vaccine, for example, people have to be informed about the known and potential benefits and risks.
Not a compulsion
- There has been an ongoing debate over whether people have the option of refusing to take the vaccine.
- Incidentally, no country has made vaccination compulsory for its people.
- Initially, all vaccines are likely to be deployed on emergency use authorizations only. Final approval from may take several months, or years.
Get an IAS/IPS ranker as your 1: 1 personal mentor for UPSC 2024
Attend Now
Note4Students
From UPSC perspective, the following things are important :
Prelims level: Hayabusa2 Probe
Mains level: Not Much
A Japanese spacecraft is nearing Earth after a yearlong journey home from a distant asteroid with soil samples. It is set to land in Australia.
Try this PYQ:
Which of the following is/are cited by the scientists as evidence/evidence for the continued expansion of the universe?
- Detection of microwaves in space
- Observation of redshirt phenomenon in space
- Movement of asteroids in space
- Occurrence of supernova explosions in space
Codes:
(a) 1 and 2 only
(b) 2 only
(c) 1, 3 and 4
(d) None of the above can be cited as evidence.
Hayabusa2 Probe
- Hayabusa2is an asteroid sample-return mission operated by the Japanese space agency, JAXA.
- It follows on from the Hayabusa mission which returned asteroid samples in 2010.
- It was launched on 3 December 2014 and rendezvoused with near-Earth asteroid 162173 Ryugu on 27 June 2018.
- It surveyed the asteroid for a year and a half and took samples. It left the asteroid in November 2019.
- It carries multiple science payloads for remote sensing, sampling, and four small rovers that investigated the asteroid surface to inform the environmental and geological context of the samples collected.
Get an IAS/IPS ranker as your 1: 1 personal mentor for UPSC 2024
Attend Now
Note4Students
From UPSC perspective, the following things are important :
Prelims level: Arunachal Kiwi
Mains level: Organic farming in India
Recently, the ‘Wild’ Arunachal Kiwi has received organic certification by the Mission Organic Value Chain Development for the North East Region.
Try this PYQ:
Q.Among the agricultural commodities imported by India, which one of the following accounts for the highest imports in terms of value in the last five years?
(a) Spices
(b) Fresh fruits
(c) Pulses
(d) Vegetable oils
Arunachal Kiwi
- The kiwifruit (Actinidia deliciosa Chev.) is a deciduous fruiting vine native to Yangtze River valley of south and central China.
- In Arunachal Pradesh, a domesticated variety of kiwi was introduced as a commercial fruit only in 2000.
- The Ziro Valley specifically located at 1,500-2,000 metres above sea level is the most ideal for kiwi.
- It is also called “China’s miracle fruit” and “Horticulture wonder of New Zealand”.
Benefits of certification
- Certification helps producers and handlers; they receive premium prices for the products and have access to fast-growing, local, regional and international markets.
Organic certification in India
- An agricultural practise/product is considered organic when there are no chemical fertilizers or pesticides involved in its cultivation process.
- Such certifications in India can be obtained after a strict scientific assessment done by the regulatory body, Agricultural and Processed Food Products Export Development Authority (APEDA).
Get an IAS/IPS ranker as your 1: 1 personal mentor for UPSC 2024
Attend Now
Note4Students
From UPSC perspective, the following things are important :
Prelims level: Zebrafish
Mains level: Not Much
Indian scientists have used the Zebrafish model and identified its genes that can promote heart regeneration.
Try this PYQ:
Q.With reference to India’s Biodiversity, Ceylon frogmouth, Coppersmith Barbet, Gray-chinned minivet and White-throated redstart are-
(a) Birds
(b) Primates
(c) Reptiles
(d) Amphibians
Zebrafish
- Zebrafish is a small (2-3 cm long) freshwater fish found in the tropical and subtropical regions.
- The fish is native to South Asia’s Indo-Gangetic plains, where they are mostly found in the paddy fields and even in stagnant water and streams.
- The fish become adults at three months and survive 2-3 years in a laboratory condition.
- Its unique characteristics lie in its transparency during its embryonic stages, allowing observing all organs, including beating heart and blood circulation.
Ability to heal their heart
- The ability of Zebrafish to heal their heart after injury makes them an attractive model to investigate mechanisms governing the regenerative process.
- Researchers worldwide are actively working to understand the mechanism behind the heart regeneration in Zebrafish for the last two decades.
- Years of efforts have helped them identify the cellular communication network factor 2a (ccn2a), a gene that can promote heart regeneration by enhancing cardiomyocyte proliferation.
- They have also observed that this gene resolves the transient collagenous fibrotic scar resulting in faster regeneration.
Significance for humans
- Cardiovascular diseases are the number 1 cause of deaths globally, taking an estimated 17.9 million lives each year, according to the World Health Organisation.
- Humans cannot regenerate their hearts upon myocardial damage and a person who suffered a heart attack cannot functionally heal the damaged heart muscle, resulting in reduced pumping efficiency.
- While on the other hand, this unique fish has the full potential to regenerate its heart and restore its function after injury.
- Till now, there is no treatment available to restore the damaged heart function in humans. Hence scientists have sought to decode the heart regeneration processes using this model animal.
Get an IAS/IPS ranker as your 1: 1 personal mentor for UPSC 2024
Attend Now
Note4Students
From UPSC perspective, the following things are important :
Prelims level: Annapurna idol
Mains level: Not Much
PM has announced that an ancient idol of the goddess Annapurna, stolen from India about a century ago, is being brought back from Canada.
Must revise: Gandhara and Mathura school of Art
[Static Revision] Chapter 6 | Post Mauryan Period (200BC to 300AD)
Annapurna Idol
- Annapurna, also spelt Annapoorna, is the goddess of food.
- This 18th-century idol, carved in the Benares was stolen from a temple of Varanasi and smuggled out around 100 years ago somewhere around 1913.
- Now is part of the University of Regina, Canada’s collection at the MacKenzie Art Gallery.
- The idol holds a bowl of kheer in one hand and a spoon in the other.
Get an IAS/IPS ranker as your 1: 1 personal mentor for UPSC 2024
Attend Now
Note4Students
From UPSC perspective, the following things are important :
Prelims level: RT-PCR, LAMP
Mains level: COVID testing issues
Indian Council of Medical Research has recently validated the LAMP technology for COVID-19 testing.
What is RT-LAMP?
- RT-LAMP stands for Reverse Transcriptase loop-mediated isothermal amplification) technology.
- Agappe Diagnostics has recently developed the technology indigenously, and their kit has been validated and approved by the ICMR for marketing.
- It is named LUME Screen nCoV.
How does it work?
- RT-LAMP technology is a one-step nucleic acid amplification method to multiply specific sequences of RNA of the coronavirus.
- The RNA is first made into cDNA (copy DNA) by the usual reverse transcription. Then, the DNA is amplified by the LAMP technique.
Current method
- •The current method diagnosis is the real time reverse transcription polymerase chain reaction (RT-PCR) test which detects the presence of viral nucleic acids in nasopharyngeal swab samples.
- But it has certain shortcomings.
- The test requires complex and costly equipment. It requires extensive training for potential users.
Benefits of LAMP over RT-PCR
- The LAMP technology is superior to the PCR technology–based COVID-19 kits where specificity is around 95% only.
- As the specificity and sensitivity of the test is about 95%, there is a possibility of false negative results.
- The turnaround time is about 10 hours, so that the result will be available only by the next day.
- In remote places, the turnaround time further increases depending on the distance the samples need to travel.
- In short, the RT-PCR does not have the capacity to keep pace with the increasing demand.
- The LAMP technology does not need laborious preparation as in the case of RT-PCR. LAMP is cost effective and does not need complex expensive equipment.
Get an IAS/IPS ranker as your 1: 1 personal mentor for UPSC 2024
Attend Now
Note4Students
From UPSC perspective, the following things are important :
Prelims level: BEOSP
Mains level: Use of technolgy in crime investigations
A brain electrical oscillation signature profiling (BEOSP) test will be conducted on the convicts of the alleged rape and murder in Hathras, Uttar Pradesh.
Note: According to Article 20(3) of the Indian constitution, no person accused of any offence shall be compelled to be a witness against himself. The privilege against self-incrimination is a fundamental canon of common criminal law jurisprudence.
What is the BEOSP test?
- BEOSP also known as brain fingerprinting is a neuro-psychological method of interrogation in which the accuser’s participation in the crime is investigated by studying their brain’s response.
- The BEOSP test is carried out via a process known as an electroencephalogram, conducted to study the electrical behaviour of the human brain.
- Under this test, the consent of the accused is first taken and they are then made to wear caps with dozens of electrodes attached to them.
- The accused are then shown visuals or played audio clips related to the crime to check if there is any triggering of neurons in their brains which then generate brainwaves.
- The test results are then studied to determine the participation of the accused in a crime.
What differentiates a BEOSP test from a polygraph or a lie detector?
- The BEOSP procedure does not involve a question-answer session with the accused and is rather a neuro psychological study of their brain.
- In a polygraph test, the accused person’s physiological indicators are taken into account which includes blood pressure, pulse rate, respiration and skin conductivity.
- While a person might be able to control their pulse rate and BP even in times of distress, a BEOSP test
Can these tests be admitted as evidence?
- Not as a standalone, a/c to the 2010 Supreme Court judgment in the Selvi v. State of Karnataka case.
- The bench observed that narco analysis, polygraph and brain mapping tests cannot be forced upon any individual without their consent and the test results cannot be admitted solely as evidence.
- However, any information or material discovered during the tests can be made part of the evidence, observed the bench.
Get an IAS/IPS ranker as your 1: 1 personal mentor for UPSC 2024
Attend Now
Note4Students
From UPSC perspective, the following things are important :
Prelims level: Brahmos Missiles
Mains level: India's missile arsenal
India’s Armed forces are conducting back-to-back tests of various versions of BrahMos missile.
Take a quick look at India’s missile arsenal:
[Prelims Spotlight] Missiles
The BrahMos Missiles
- A combination of the names of Brahmaputra and Moskva rivers, BrahMos missiles are designed, developed and produced by BrahMos Aerospace, a joint venture company set up by DRDO and Mashinostroyenia of Russia.
- It is a two-stage missile with a solid propellant booster as the first stage and liquid ramjet as the second stage.
- The cruise missiles like BrahMos are a type of systems known as the ‘standoff range weapons’ which are fired from a range sufficient to allow the attacker to evade defensive fire from the adversary.
- These weapons are in the arsenal of most major militaries in the world.
- The versions of the BrahMos that are being tested have an extended range of around 400 km, as compared to its initial range of 290 km, with more versions of higher ranges currently under development.
Various versions
- Various versions of the BrahMos, including those which can be fired from land, warships, submarines and Sukhoi-30 fighter jets have already been developed and successfully tested in the past.
- The earliest versions of the ship launched BrahMos and land-based system are in service of the Indian Navy and the Indian Army since 2005 and 2007 respectively.
Get an IAS/IPS ranker as your 1: 1 personal mentor for UPSC 2024
Attend Now